Intra-Golgi transport
The Golgi modifies cargo as it moves through the organelle. How is that traffic coordinated with the recycling of its resident proteins?
Cell transport
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Bulky cargo export from the ER
Some cargo is too large for a conventional small transport vesicle. How does it leave the endoplasmic reticulum?
Nuclear pore selectivity
Nuclear pores admit some molecules and exclude others. How does their dynamic central barrier adjust to the cargo passing through?
Spore hydration
Dormant bacterial spores take up water as they restart. Does GerAB provide a water route in Bacillus subtilis?
Paulinella protein import
A Paulinella amoeba carries a photosynthetic compartment descended from a bacterium. It makes essential proteins outside that compartment—how do those proteins cross its inner membrane to work inside?
Outer membrane vesicle cargo selection
A bacterium releases membrane bubbles whose protein contents differ from its own envelope. What determines which proteins leave in those bubbles and which stay behind?