Mammalian cell size homeostasis
Different mammalian cells maintain different sizes. What sets their target size and coordinates growth with division?
Cell growth and division
The coordination of cell size, DNA copying, and chromosome separation.
A few problems to explore
3 totalMitotic spindle self-organization
Spindles organize filaments to separate chromosomes. How do chromosome-attached bundles integrate with the spindle’s collective organization?
Mammalian replication origins
Mammalian DNA replication can begin at many licensed sites. What determines which sites actually start copying in a given cell?