Alzheimer’s disease
Amyloid, tau, immune activity, and other changes accompany Alzheimer’s disease. How do they interact to cause neuronal dysfunction, and why does the course differ between people?
Disease mechanisms
The biological processes that cause or sustain disease.
A few problems to explore
7 totalParkinson’s disease
Parkinson’s disease affects multiple cells and systems, yet people develop it through different combinations of risks. What drives the damaging processes and their spread?
Long COVID
Some people experience persistent or new health problems after SARS-CoV-2 infection. Which biological processes sustain these different conditions?
Tumor dormancy
Cancer cells can persist quietly for years and later form a new tumor. What keeps them dormant, and what allows them to start growing again?
Malaria relapse
Plasmodium vivax can remain dormant in the liver before causing malaria again. What makes the parasite restart replication?
Multiple sclerosis relapse
EBV-related immune activity can rise before multiple sclerosis relapses. Does it drive new brain and spinal-cord lesions, amplify another trigger, or accompany it?